Syphilis rapid test is a quick diagnostic tool used to detect the presence of Treponema pallidum (TP), the bacterium responsible for syphilis. By detecting the Treponemal antibodies (IgG and IgM) the test will indicate a current or past syphilis infection within 10-30 minutes.

The Synthgene® Syphilis Test is a lateral flow chromatographic immunoassay for the qualitative detection of anti-Treponema pallidum (T. pallidum) in human whole blood, serum or plasma specimens. Only three drops of human plasma/spine (approximately 75ul) or two drop of human whole blood (fingertip blood or venous blood) (approximately 50ul) are required to perform this test. As finger prick is sufficient for the sample it makes the testing process minimally invasive and easy to administer.  The results will be observed in 10 minutes and will be effective within 30 minutes. The test procedure requires no special training or qualification.

Syphilis is sexually transmitted, and can also be passed on from a mother to her fetus during pregnancy. Most persons with syphilis tend to be unaware of their infection and they can transmit the infection to their sexual contacts or, in the case of a pregnant woman, to her unborn child. If left untreated, syphilis can cause serious consequences such as stillbirth, prematurity and neonatal deaths. Early detection and treatment is also critical in preventing severe long term complications in the patient and onward transmission to sexual partners.

How is syphilis diagnosed. Since most patients with syphilis have no symptoms or signs, diagnosis relies on a blood test for the detection of antibodies. The antibody response to T. pallidum can be detected within 4 to 7 days after the syphilis chancre appears, allowing the early detection and diagnosis of a syphilis infection. These are simple point of care tests and can be performed outside a laboratory setting with minimal training and no equipment using a small amount of whole blood collected by a finger prick.

Result interpretation

Positive: Red bands appear in both the detection area (T) and the control area (C). The results show that the sample contains syphilis antibodies.

Negative: There is no red band in the detection area (T), and a red band appears in the control area (C). The results show that syphilis antibodies are not detected in the sample.

Invalid: No red band appears in the control area (C), regardless of whether there is a red band in the detection area (T), the test pad is judged to be invalid, and it is recommended to perform a retest.

Note: Do not read the results in dimly lit places. It is recommended not to make any medically related decisions without first consulting a healthcare provider.

The test is highly sensitive and specific, but false positives and negatives can occur:

False positives: May be due to other infections, autoimmune diseases, or pregnancy.

False negatives: Can occur in early primary syphilis or in late untreated syphilis.

Operation Suggestions

1. This product is only used for in vitro qualitative diagnosis, please use it within the validity period.
2. Please read the instruction manual carefully before use, and carry out the test operation in strict accordance with the kit instructions.
3. The product is for one-time use. If the aluminum foil bag is found to be damaged, please do not use it. All samples and used products should be treated as infectious agents. Follow the local regulations on safe disposal of waste and infectious waste.Please handle with caution.
4. If the test reagents stored in the refrigerator are used, it is recommended that they should be taken out of the refrigerator before the test and placed at room temperature before opening for use, otherwise the test results will be affected.
5. If there is unknown drug interference or technical reasons for operation, the results will be wrong; if the results are in doubt, please re-test.

Expiration date: Feb. 2026